Antidepressant

What is an Antidepressant?

Antidepressants are medications used to treat depression and some other mental health conditions. These drugs help improve mood by affecting brain chemicals (neurotransmitters). Here are some basic facts you should know about antidepressants:

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Types of Antidepressants

Antidepressants are divided into various types with different mechanisms and effects:

Selective Serotonin Reuptake Inhibitors (SSRIs):

  • They improve mood by increasing serotonin levels. Common examples include fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro).

Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs):

  • They act by blocking the reuptake of both serotonin and norepinephrine (another neurotransmitter). Venlafaxine (Effexor) and duloxetine (Cymbalta) belong to this group.

Tricyclic Antidepressants (TCAs):

  • An older type of antidepressants effective on serotonin and norepinephrine. Amitriptyline and nortriptyline are well-known examples.

Monoamine Oxidase Inhibitors (MAOIs):

  • They work by inhibiting an enzyme that breaks down neurotransmitters. This group is less commonly preferred because of interactions with some foods and drugs. Phenelzine (Nardil) is an example in this group.

Other Antidepressants:

  • Medications like bupropion (Wellbutrin) and trazodone work with different mechanisms and are used in antidepressant treatment.

Uses of Antidepressants

  • Depression: Mainly used to treat major depression.
  • Anxiety Disorders: Can be effective in generalized anxiety disorder, social anxiety, and panic disorder.
  • Obsessive-Compulsive Disorder (OCD): Sometimes used in the treatment of this disorder.
  • Eating Disorders: May help in conditions such as bulimia and anorexia.
  • Emotional Disorders: Can be beneficial in some cases like post-traumatic stress disorder (PTSD).

Side Effects of Antidepressants

Antidepressants may have some side effects which vary among individuals. Common ones include:

  • Nausea
  • Dizziness
  • Sleep disturbances (insomnia or excessive sleep)
  • Dry mouth
  • Sexual dysfunction
  • Variable appetite

Precautions While Using

  • Medical Supervision: It is important to consult a healthcare professional before starting antidepressants. This helps choose the right type and dosage.
  • Consult Your Doctor Later: If you experience side effects or feel the medication is ineffective, inform your doctor.
  • Discontinuation of Medication: Suddenly stopping antidepressants can cause withdrawal symptoms or relapse. It is very important to get doctor’s advice before stopping.

Alternative and Complementary Methods

In addition to antidepressant treatment, other therapies can help:

  • Cognitive behavioral therapy (CBT)
  • Support groups
  • Exercise
  • Healthy nutrition
  • Meditation and stress management techniques

The period of antidepressant use is complex and personal, so it is always safest to proceed under the guidance of a professional healthcare provider.

Prepared by A Life Medical Editorial Board.

Last Updated: 6 Kasım 2025 14:05

Publish Date: 4 Ağustos 2024 00:15

Antidepressant

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